The article reviews existing scientific literature on the anticancer and immune-boosting properties of Astragalus root and Shiitake mushrooms. The authors propose a novel method of cultivating Shiitake mushrooms on Astragalus-enriched beds, which may enhance the transfer and bioavailability of beneficial Astragalus polysaccharides into the mushrooms, potentially leading to a functional food with combined therapeutic effects.
The article examines the traditional uses and pharmacological properties of Astragalus membranaceus, highlighting its potential anti-aging benefits. The authors discuss how compounds such as polysaccharides, flavonoids, and saponins contribute to its antioxidant, anti-inflammatory, and immunoregulatory effects, which may play roles in lifespan extension and the prevention of age-related diseases.
A study investigated the effects of Cycloastragenol and Astragaloside IV, compounds derived from the herb Astragalus membranaceus, on nucleus pulposus cells exposed to high glucose conditions. The findings revealed that these compounds activated telomerase, reduced cellular senescence and apoptosis, and improved cell viability, suggesting their potential therapeutic role in managing diabetes-induced intervertebral disc degeneration.
This study investigates natural compounds, including those from Astragalus, for their ability to activate telomerase, supporting telomere length preservation and anti-aging effects
A study evaluated the effects of a multi-component hydroethanolic root extract (HRE) of Astragalus mongholicus Bunge on telomere length in peripheral blood lymphocytes from 18 healthy donors aged 32 to 86 years. The findings revealed that HRE treatment led to significant telomere elongation with less toxicity compared to danazol, suggesting its potential for managing age-related […]
A study investigated the effects of Astragalus polysaccharides (APS) on epileptogenesis, cognitive impairment, and neuroinflammation in a pentylenetetrazole-induced kindling mouse model. The results demonstrated that APS administration reduced seizure severity, improved cognitive function, and decreased neuroinflammatory responses, suggesting its potential therapeutic role in epilepsy management.
A randomized, double-blind, placebo-controlled study investigated the effects of an Astragalus-based nutritional supplement on telomere length in 40 healthy middle-aged adults over six months. The findings revealed that participants taking the supplement experienced significant increases in both median and short telomere lengths, suggesting the supplement’s potential role in promoting healthy aging.
