The article examines how C60 fullerene reduces oxidative stress and mitochondrial dysfunction caused by 3-nitropropionic acid in rats by modulating key proteins such as p53, Bcl-2, and Nrf2. In the C60a formula, this research supports its potential in enhancing mitochondrial health, reducing cellular stress, and promoting longevity. This study directly aligns with the C60a product’s goal of protecting cells from oxidative damage and supporting overall vitality.