The article examines the health benefits of β-glucans found in edible mushrooms. It highlights that while β-glucans from oats and barley have been shown to improve cardiovascular health by enhancing glucose and lipid metabolism and lowering blood pressure, similar effects from mushroom-derived β-glucans require further confirmation through human studies. Additionally, mushrooms contain other beneficial components, such as bioactive phenolic compounds, vitamins, and minerals, which may also contribute to cardiovascular protection.