A systematic review and meta-analysis of randomized clinical trials examined the effects of apple cider vinegar (ACV) on lipid profiles and glycemic parameters. The analysis revealed that ACV consumption significantly reduced serum total cholesterol by approximately 6.06 mg/dL, fasting plasma glucose by 7.97 mg/dL, and HbA1C levels by 0.50%, indicating potential benefits in managing blood lipid levels and glycemic control.