The examines zinc’s essential role in the immune system, highlighting that zinc deficiency impairs both innate and adaptive immunity, leading to increased susceptibility to infections. It discusses how adequate zinc levels are crucial for the normal development and function of immune cells such as neutrophils, natural killer cells, T lymphocytes, and B lymphocytes, and emphasizes that zinc deficiency can compromise various immune responses, including skin barrier integrity, gene regulation within lymphocytes, and macrophage function.