Spasmolytic Effects of Aphanizomenon Flos Aquae (AFA) Extract on the Human Colon Contractility
The study investigated the impact of Klamin®, an extract from the blue-green algae Aphanizomenon flos-aquae (AFA), on human colon muscle contractions. The findings revealed that Klamin® significantly reduced spontaneous contractions of the colon by activating trace-amine-associated receptor 1 (TAAR1) through its β-phenylethylamine (β-PEA) content, leading to serotonin release from enteric neurons, suggesting its potential as […]
AphaMax®, an Aphanizomenon Flos-Aquae Aqueous Extract, Exerts Intestinal Protective Effects in Experimental Colitis in Rats
The study investigates the therapeutic potential of AphaMax®, a concentrated extract from the blue-green algae Aphanizomenon flos-aquae, in a rat model of colitis induced by 2,4-dinitrobenzenesulfonic acid (DNBS). The findings demonstrated that preventive oral administration of AphaMax® significantly reduced the severity of colitis, as evidenced by improvements in clinical signs, macroscopic and microscopic colon damage, […]
Effects of blue-green algae extracts on the proliferation of human adult stem cells in vitro
The preliminary study investigates the impact of extracts from the blue-green algae Aphanizomenon flos-aquae (AFA) on human stem cell proliferation. The researchers found that while AFA extracts alone had moderate effects, combining an ethanol extract of AFA cellular concentrate with the nutraceutical formulation NT-020 significantly enhanced the proliferation of human bone marrow and CD34+ hematopoietic […]
AFA and CD34+ Hematopoietic Stem Cell Mobilization
A study investigated the impact of consuming Aphanizomenon flos-aquae (AFA), a type of blue-green algae, on the mobilization of CD34+ hematopoietic stem cells (HSCs) in healthy individuals. The results indicated that short-term consumption of AFA extract over 48 hours significantly increased the number of circulating CD34+ cells, suggesting that AFA may effectively promote HSC mobilization.
AFA Algae: Antioxidant and Neuroprotective Benefits
Aphanizomenon flos-aquae (AFA), a type of blue-green algae, has demonstrated significant antioxidant and neuroprotective properties. Studies indicate that AFA extract can mitigate neurodegeneration by reducing insulin resistance, decreasing neuronal loss, and modulating the activation of astrocytes and microglia, which are crucial for maintaining brain health.