The multipartite mitochondrial genome of Fallopia multiflora (Caryophyllales: Polygonaceae)
The study reports that the mitochondrial genome of F. multiflora comprises two circular chromosomes measuring 200,352 and 112,098 nucleotides, respectively. These chromosomes collectively encode 57 genes, including 34 protein-coding genes, 20 transfer RNA genes, and three ribosomal RNA genes. Phylogenetic analysis indicates that F. multiflora is closely related to Beta macrocarpa and Silene latifolia. The […]
The first chromosome-level Fallopia multiflora genome assembly provides insights into stilbene biosynthesis
The study reports the successful assembly of the F. multiflora genome at the chromosome level, totaling 1.46 gigabases. Through integrated genomic, transcriptomic, and metabolomic analyses, the researchers identified two FmRS genes responsible for catalyzing the formation of resveratrol, a stilbene compound with notable pharmacological activities, thereby enhancing the understanding of stilbene biosynthesis pathways in this […]
Review of clinical studies of Polygonum multiflorum Thunb
It highlights the herb’s potential benefits in treating conditions like liver injury, neurodegenerative diseases, and alopecia, while also addressing concerns regarding hepatotoxicity reported in clinical cases.
Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb
The review article titled “Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb.” provides a comprehensive overview of this traditional Chinese medicinal plant, commonly known as He Shou Wu. The authors discuss its traditional applications, including anti-aging and hair-darkening effects, and delve into its phytochemical constituents such as stilbenes, quinones, and flavonoids. The […]
Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds
The article examines the therapeutic benefits and potential hepatotoxicity of Polygonum multiflorum (commonly known as He shou wu or Fo-ti), a traditional Chinese medicinal herb used for conditions such as liver injury, cancer, diabetes, alopecia, atherosclerosis, and neurodegenerative diseases. The review highlights various clinical studies, discussing the herb’s pharmacokinetics, pharmacodynamics, and therapeutic assessments, while also […]